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2 OMIM references -
2 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 1

Wilson-Turner syndrome

1 OMIM reference -
1 associated gene
38 signs/symptoms

Cap myopathy

Wilson-Turner syndrome

TPM2	(UniProt - OMIM)		HDAC8	(UniProt - OMIM)
TPM3	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	TPM3	(0.72)	HDAC8

Citations in the biomedical literature:

Cap myopathy		Wilson-Turner syndrome
	Synonym(s): - Cap disease		Synonym(s): - X-linked intellectual deficit - gynecomastia - obesity

	Classification (Orphanet): - Rare genetic disease - Rare neurologic disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare endocrine disease - Rare genetic disease - Rare neurologic disease

	Classification (ICD10): - Diseases of the nervous system -		Classification (ICD10): (no data available)

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: childhood Average age of death: - Type of inheritance: x-linked dominant

	External references: 2 OMIM references - No MeSH references		External references: 1 OMIM reference - No MeSH references

Wilson-Turner syndrome
	Very frequent - Generalized obesity Frequent - Gynecomastia / breast / mammary gland enlargement / hyperplasia - Small / atrophic / hypoplastic testes / monorchism / microorchidism / anorchia - Speech troubles / aphasia / dysphasia / echolalia / mutism / logorrhea / dysprosodia Occasional - Abnormal cry / voice / phonation disorder / nasal speech - Abnormal gait - Anodontia / oligodontia / hypodontia - Arthritis / synovitis / synovial proliferation - Ataxia / incoordination / trouble of the equilibrium - Brachycephaly / flat occiput - Coarse face - Hirsutism / hypertrichosis / Increased body hair - Hypotrichosis / atrichia / atrichiasis / scalp hairlessness - Intellectual deficit / mental / psychomotor retardation / learning disability - Irregular length / shape of fingers - Long / large ear - Lymphedema - Maternal hypertension / eclampsia / preeclampsia / gravidic toxemia - Micropenis / small penis / agenesis - Microstomia / little mouth - Microtia / cryptomicrotia / anotia / external auditory canal / pinnae aplasia / hypoplasia - Pointed chin - Preauricular / branchial tags / appendages - Prognathism / prognathia - Protruding lips - Round ear - Scoliosis - Seizures / epilepsy / absences / spasms / status epilepticus - Small hand / acromicria - Small / hypoplastic / adherent / absent ear lobe - Spindle shaped fingers - Striae - Synophris / synophrys - Tapered fingers - Thick / bushy eyebrows - Thick / wide ear lobe - Umbilical hernia - Undescended / ectopic testes / cryptorchidia / unfixed testes
Cap myopathy
(no data available)